More On Dichloroacetate, Potential Cancer Cure

By Justin Gardner | Related entries in Drugs, Science

We’ve written about dichloroacetate before, but I thought I’d point it out again because it’s a wonder why we’re not hearing about it the media at large.

From the University of Alberta:

DCA is an odourless, colourless, inexpensive, relatively non-toxic, small molecule. And researchers at the University of Alberta believe it may soon be used as an effective treatment for many forms of cancer.

Dr. Evangelos Michelakis, a professor at the U of A Department of Medicine, has shown that dichloroacetate (DCA) causes regression in several cancers, including lung, breast, and brain tumors.

Michelakis and his colleagues, including post-doctoral fellow Dr. Sebastian Bonnet, have published the results of their research in the journal Cancer Cell.

Scientists and doctors have used DCA for decades to treat children with inborn errors of metabolism due to mitochondrial diseases. Mitochondria, the energy producing units in cells, have been connected with cancer since the 1930s, when researchers first noticed that these organelles dysfunction when cancer is present.

Until recently, researchers believed that cancer-affected mitochondria are permanently damaged and that this damage is the result, not the cause, of the cancer. But Michelakis, a cardiologist, questioned this belief and began testing DCA, which activates a critical mitochondrial enzyme, as a way to “revive” cancer-affected mitochondria.

Hello MSM? Where are you? You’ll speculate for days upon days about who’ll get custody of Anna Nicole Smith’s daughter, but you can’t do a couple pieces on this?

Also, here are a couple posts that are skeptical about dichloroacetate.


This entry was posted on Monday, May 14th, 2007 and is filed under Drugs, Science. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.

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